Edgars ABELE

edgars.jpg (45880 bytes) Dr.habil.chem. Edgars Abele

Latvian Institute of Organic Synthesis
Aizkraukles 21, Riga, LV-1006, Latvia

Phone: (371) 7551822
Fax: (371) 7550338
E-mail: abele@osi.lv

Born: January 22, 1962, Riga, Latvia

Interests:

Scientific publications: ~ 160

Education:

 

Experience: 

Recent representative publications (2000-2007):

  1. E. Abele, K. Rubina, O. Arsenyan, S. Grinberga, J. Popelis, E. Lukevics. Fluoride ion-mediated reactions of disubstituted acetylenes Me3SiC CMMe3 (M = C, Si, Ge, Sn) with aldehydes and ketones. - Main Group Metal Chem., 2000, vol. 23, N 4, pp. 243-252. 
  2. E. Abele, R. Abele, J. Popelis, E. Lukevics. Novel stereoselective synthesis of E-aryl aldoxime and ketoxime O-ethers. - Org. Prep. Proced. Int.2000, vol. 32, N 2, pp. 153-159.
  3. K. Rubina, E. Abele, P. Arsenyan, R. Abele, M. Veveris, E. Lukevics. Synthesis of silicon and germanium containing heteroaromatic sulfides as cholesterol level lowering and vasodilating agents. - Metal-Based Drugs,   2001, vol. 8, N 2, pp. 85-93. 
  4. E. Abele, M. Fleisher, K. Rubina, R. Abele, E. Lukevics. Halogenation of terminal acetylenes by perhalogenalkanes under phase transfer catalysis conditions. - J. Molecular Catalysis A: Chemical., 2001, vol. 165, N 1-2, pp. 121 – 126.
  5. E. Lukevics, K. Rubina, E. Abele, M. Fleisher, P. Arsenyan, S. Grinberga, J. Popelis. Fluoride ion – mediated reactions of disubstituted acetylenes Me3SiCCMMe3 (M = C, Si, Ge, Sn) with terminal acetylenes. - J.  Organomet. Chem., 2001, vol. 634, N 1, pp. 69-73.
  6. E. Abele, O.Dzenitis, K. Rubina, E. Lukevics. Synthesis of N- and S-vinyl derivatives of heteroaromatic compounds using phase transfer catalysis. - Chem. Heterocycl. Comp.,  2002, vol. 38, N 6, pp. 682-685.
  7. E. Abele, K. Rubina, R. Abele, O. Dzenitis, P. Arsenyan, J. Popelis, M. Veveris, D. Meirena, E. Lukevics. Silacyclic derivatives of heteroaromatic sulfides as selective cholesterol level lowering and vasodilating agents. - Metal-Based Drugs, 2002, vol. 8, N 6, pp. 307-313.
  8. E. Abele, K. Rubina, M. Fleisher, J. Popelis, P. Arsenyan, E. Lukevics. Synthesis of unsymmetric diynes by palladium catalyzed coupling of terminal bromoalkynes with alkynylstannanes.-  Appl. Organomet. Chem., 2002, vol 16, N 3, pp. 141-147.
  9. R. Abele, E. Abele, K. Rubina, O. Dzenitis, P. Arsenyan, I. Shestakova, A. Nesterova, I. Domracheva, J. Popelis, S. Grinberga, E. Lukevics. Synthesis and cytotoxicity of 3-(hetarylthio)-1-propynyl(trimethyl)silanes. -  Chem. Heterocycl. Comp., 2002, vol. 38, N 7, pp. 867-872.
  10. E. Abele, O. Dzenitis, J. Popelis, E. Lukevics. Novel fluoride ion mediated method for rapid silylation of carboxylic acids with azidotrimethylsilane under phase transfer catalysis conditions. - Main Group Metal Chemistry, 2002, vol. 25, pp. 585-587.
  11. E. Lukevics, E. Abele, P. Arsenyan, R. Abele, K. Rubina, I. Shestakova, I. Domracheva, V. Vologdina. Synthesis and cytotoxicity of silicon containing pyridine and quinoline sulfides. - Metal-Based Drugs,  2002, vol. 9, N 1-2, pp. 45-51.
  12. R. Abele, E. Abele, M. Fleisher, S. Grinberga, E. Lukevics. Novel fluoride ion mediated synthesis of unsymmetric siloxanes under phase transfer catalysis conditions. - J. Organomet. Chem., 2003, vol 686, pp. 52-57.
  13. P. Arsenyan, K. Rubina, I. Shestakova, E. Abele, R. Abele, I. Domracheva, A. Nesterova, J. Popelis, E. Lukevics, Synthesis and cytotoxicity of silylalkylthio-substituted N-heterocycles and their hydroselenites . - Appl. Organomet. Chem., 2003, vol. 17, pp.825-830.
  14.   K. Rubina, M. Fleisher, E. Abele, J. Popelis, E. Lukevics, Prototropic rearrangement of N-, O- and S-propargyl derivatives under phase transfer catalysis conditions: mechanisms and limitations . -  Zh. Org. Khim., 2003, vol. 39, N 7, pp.1024-1028 (in Russian).
  15. K. Rubina, E. Abele, J. Popelis, S. Grinberga, P. Arsenyan, E. Lukevics. Novel stereoselective phase transfer catalytic synthesis and some applications of (E)-2-chlorovinylthioarenes and hetarenes. -  Phosphorus, Sulfur, and Silicon and the Related elements, 2003, vol. 178, N 3, pp. 531-529.
  16. K. Rubina, E. Abele, P. Arsenyan, M. Fleisher, J. Popelis, A. Gaukhman, E. Lukevics, The role of palladium catalyst and base in stereoselective transformations of (E)-2-chlorovinylsulfides. - Tetrahedron, 2003, vol. 59, pp. 7603-7607.
  17. E. Abele, R. Abele, P. Arsenyan, I. Shestakova, I. Kanepe, I. Antonenko, J. Popelis, E. Lukevics. Synthesis and cytotoxicity of silicon and germanium containing pyridine oxime O-ethers . - Bioinorg. Chem. Appl., 2003, vol. 1, N 3-4, pp. 299-308.
  18. E. Abele, R. Abele, P. Arsenyan, E. Lukevics. A new pathway for the preparation of diaryl acetylenes. - Tetrahedron Letters, 2003, vol. 44, N 20, pp. 3911-3913.
  19. R. Abele, L. Zvejniece, E. Abele, K. Rubina, P. Arsenyan, M. Vandish, O. Pudova, M. Dambrova, I. Domracheva, I. Shestakova, J. Popelis, E. Lukevics. Synthesis and neurotropic activity of silyl propargyl alcohols and sulfides. - Appl. Organomet. Chem. , 2004, vol. 18, N 4, pp. 181-186.
  20. E. Abele, J. Popelis, I. Shestakova, I. Domracheva, P. Arsenyan, E. Lukevics. Synthesis and cytotoxicity of derivatives of di(3-indolyl)selenides -  Chem.Heterocycl. Comp. (Engl. Ed.), 2004, vol. 40, N6, 742-746. 
  21. P.Arsenyan , R.Abele, S. Belyakov, E.Abele, E.Lukevics.  The crystal structure of   bis-(3,3dimethyl-3,4-dihydro-2H-1-thia-4a,9-diaza-3-sila-fluorene) silver nitrate. - Appl. Organomet. Chem.,  2005, vol. 19, N 7, pp.875-876.  
  22. E.Abele, K.Rubina, S.Belyakov, M.Fleisher, J.Popelis. Unusual protonation of oxime nitrogen in acetophenone O-[3-(5-tetrazolyl)propyl]oxime in solid state. - Heterocycl. Commun., 2006, 12(3-4), 259-264.   
  23. E.Abele, M.Veveris, R.Abele, K.Rubina, P.Arsenyan, D.Meirena. 3-(Hetarylthio)-1-propynyl(dimethylalkyl) silanes as selective cholesterol level lowering agents. - Main Group Met.Chem.,  2006, vol. 29, N 4, pp. 215-219.  

 

Reviews

  1. E. Abele, E. Lukevics. Reactions of carbon tetrachloride and carbon tetrabromide with anions and carbanions.  -  Org. Prep. Proced. Int. – 1999. – Vol. 31, N 4. – P. 359-377.
  2. E. Abele, E. Lukevics, Recent advances in the chemistry of oximes.   -  Org. Prep.Proced. Int. – 2000. – Vol. 32, N 3. – P. 235-264.
  3. E. Abele, E. Lukevics. Recent advances in the synthesis of heterocycles from oximes. -  Heterocycles, - 2000. – Vol. 53, N 10 – P. 2285-2336.
  4. E. Abele, E. Lukevics. Recent advances in asymmetric phase transfer catalysis.  -  Latv.J.Chem., - 2001. - Nr. 1. - pp. 3.-14. 
  5. E. Abele, E. Lukevics. Recent advances in transition metal-catalyzed coupling reactions of silanes under fluoride ion activation. -  Latv.J.Chem.,   2001, N 4, pp. 327-328.  
  6. E. Abele, E. Lukevics. Recent advances in fluoride ion activation of silicon bonds in organic synthesis. - Main Group Met. Chem. - 2001. - Vol. 24, Nr. 6. - P. 315- 350.
  7. E. Abele, E. Lukevics. Recent advances in the synthesis and transformations of heterocycles mediated by fluoride ion activated organosilicon compounds. - Heterocycles,  2002, vol 57, N 2, pp. 361-404.
  8. E.Abele, R.Abele, K.Rubina, E.Lukevics.   Quinoline oximes: synthesis, reactions, and biological activity: [review].   - Chem.Heterocycl. Comp. (Engl. Ed.)., 2005, vol. 41, N 2, pp.137-162.   
  9. E. Abele. Activation of silicon bonds by fluoride ion in the organic synthesis in the new Millenium: [a review]. - - Main Group Met.Chem., 2005, 28(2), pp. 45-69. 
  10.   E. Abele, R.Abele, E. Lukevics.   Oximes of five-membered heterocyclic compounds with two heteroatoms. 1. Synthesis and structure [Review] .  -   Chem.Heterocycl. Comp. (Engl. Ed.)., 2007, vol. 43, N 4, pp. 387-407.  

Research Projects:



Last update 29.10.2007