Dr. habil. med. Jekaterina ERENPREISA
Latvian Biomedical Research and Study Centre

Ratsupites iela 1,
Riga, LV-1067

Phone: +371 67808220
Fax: +371 67442407

Born: February 13, 1945, Dnepropetrovsk, Ukraine


Brief Description of Main Results

1.    Basic research and development of new methods (approx. 16) in light and EM cytochemistry of cell nucleus.
2.    Studies of cell nucleus revealed co-operative character of levels of the chromatin organisation. In addition, discovered (1) Fractality of the rosette-like high level chromatin packaging (1989-1993); (2) Oscillatory character of the nuclear response  to damage stress (1990-1993).
3.    Staining properties of tumour cell chromatin were found associated with superhelicity of DNA.
4.    Transdifferentiation in development and induction of differentiation in tumours were shown to involve asymmetric cell  divisions and apoptosis.
5.    Aberrant cell cycle and cell death were found to have common features in embryonic development and tumours.
6.    Survival of the DNA damage-resistant tumours is likely due to the activation of the meiosis-like program in endopolyploid cells (1998- ).

Languages: English, Latvian, Russian (French, German)




Latvian Institute of Experimental and Clinical Medicine:

A.Kirchenstein Institute of Microbiology and Virology, Riga:

Biomedical Research and Study Centre,  Riga

Honours and Awards

Professional Activities and Memberships

Representative Publications:

189 scientific publications, among them 1 monography, 93 original articles (50 are indexed in PubMed).

 Participation in International Conferences:

    45 European and International Congresses and Conferences, 1989-2006.

Present International collaboration -

Recent Research Projects:

Local (supported by the Latvian Council of Science ):

English-Latvian FSU joint projects (supported by the Royal Society of London):

Bilateral Germany-Latvia BMBF project (2006-2007): “Spatial organisation of genomes and homologous chromosomes in endopolyploid tumour cells”

USA-Latvian visits exchange project (2005):

 Determination of clonogenic survival capacity and its origin in tumor cells undergoing mitotic catastrophe: implication for radiation treatment (head of the Latvian part)..

Last update 29.02.2008